Joseph was married to Eleanor Kennedy and had eight daughters and two sons. He died in 1822 in Jefferson, Tennessee at the age of 74.
His parents, Issac McCulloch (the spelling of the surname is spelled both McCulloch and McCullough in the family) and Mary Robinson, are buried at the Waxhaw Cemetery in Lancaster, South Carolina.
|Here lies ye body of Issac McCulloch, who departed life in ye 73 year of age 1780 RD|
|Here lies the body of Margaret McCulloch, who departed this life in ye 41year of her age Jan 13th 1759|